At a Glance

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Chew Sek-Jin Award Lecture 【Session Room 1】14-Sep 11:20-12:20

Professor Earl L. Smith III
Christine Wildsoet
Kyoko Ohno-Matsui
Professor Earl L. Smith III
Dean, College of Optometry, University of Houston
Title of Lecture:
Do low ambient lighting levels promote the development of myopia in primates?
A variety of observations suggest that low ambient lighting levels could put the eye at risk for developing myopia. We investigated the effects of low ambient lighting on normal refractive development and deprivation- and defocus-induced ametropias in infant monkeys. Specifically, 29 rhesus monkeys were housed under dim ambient lighting (5-36 lux) maintained on a 12 hour lights-on/12 lights-off cycle from 24 to 154 days of age. During the dim light (DL) period, animals were allowed unrestricted vision (n=7) or were reared wearing monocular diffusers (n=7), or either monocular -3D (n=7) or +3D spectacle lenses (n=8). Comparison data were obtained from age-matched control animals that were subjected to the same rearing strategies, but housed under typical laboratory lighting levels (~350 lux). The DL regimen resulted in more variable, but relative hyperopic, ametropias in animals reared with unrestricted vision. DL did not alter the course of form-deprivation myopia; however, it did reduce the likelihood that animals reared with either -3D or +3D of imposed anisometropia would exhibit compensating anisometropic growth. Data from both the treated and fellow-control eyes of lens-reared monkeys suggested that DL diminished the normal response to myopic defocus. Thus, DL appears to reduce the efficiency of emmetropization and, in the case of lens-treated monkeys, the ability of myopic defocus to slow ocular growth. Thus, DL can increase the risk of myopia.

ZEISS Young Investigator Award in Myopia Research 2019 &
Josh Wallman Memorial Lecture 【Session Room 1】12-Sep 10:45-11:45

Dr. Virginie J.M. Verhoeven
Christine Wildsoet
Kyoko Ohno-Matsui
Dr. Virginie J.M. Verhoeven
Erasmus Medical Center
Title of Lecture:
A Decade of Human Myopia Genetics Research:
Big data, Big questions
The knowledge on the genetic background of refractive error and myopia has expanded dramatically in the past few years. To date, almost 200 genetic loci have been identified for refractive error and myopia, and risk variants mostly carry low risk but are highly prevalent in the general population. Several genes for secondary syndromic myopia overlap with those for common myopia. Polygenic risk scores show overrepresentation of high myopia in the higher deciles of risk. Annotated genes have a wide variety of functions, and all retinal layers appear to be sites of expression. The current genetic findings offer a world of new molecules involved in myopiagenesis. As the missing heritability is still large, further genetic advances including large-scale, in-depth genetic studies using complementary big data analytics, consideration of gene-environment effects by thorough measurement of environmental exposures, and focus on subgroups with extreme phenotypes and high familial occurrence are needed. Functional characterization of associated variants is simultaneously needed to bridge the knowledge gap between sequence variance and consequence for eye growth.


Symposium 1

National Myopia Prevention and Control Policies - An Update

Ian Morgan
(Australian National University)
Kyoko Ohno-Matsui
(Tokyo Medical and Dental University)
Introduction. What are the options?
Ian Morgan
(Australian National University)
Myopia prevention and control in Taiwan
Pei-Chang Wu
(Kaohsiung Chang Gung Memorial Hospital)
Myopia prevention and control in Singapore
Seang-Mei Saw
(National University of Singapore)
Progress towards defining a myopia prevention and control strategy for mainland China
Mingguang He
(University of Melbourne)
The Strategy for Myopia Control and Prevention in the UK
Nicola Logan
(Aston University)
Updates of treatment for Myopic Medical/Surgical Complications
Yasushi Ikuno
(Ikuno Eye Center)
Symposium 2

International Myopia Institute: the possibilities and the probabilities

Serge Resnikoff
(Brien Holden Vision Institute)
Earl L. Smith III
(University of Houston)
Monica Jong
(Brien Holden Vision Institute)
Daniel I. Flitcroft
(University Coll. Dublin and Dublin Inst. of Technology)
David Troilo
(SUNY Coll. of Optometry, State University of New York)
Christine F. Wildsoet
(UC Berkeley)
Nicola S. Logan
(Aston University)
Caroline C. W. Klaver
(Radboud University Medical Center)
Kate L. Gifford
(Queensland University of Technology)
Jacinto Santodomingo-Rubido
(Menicon Company Limited)
Lyle Gray
(Glasgow Caledonian University)


Oral 1【Session Room 1】12-Sep 8:15-9:03

Prevalence, Progression and Biometric Changes

James Loughman
(Centre for Eye Research Ireland,
 Technological University Dublin)
Nicola Logan
(Aston University)
Application of Big-Data for Epidemiological Studies of Refractive Error
Michael Moore
Potential Value of Centile Analysis in Eye Growth and Refractive Development
Daniel I. Flitcroft
The Progression of Myopia before the Age of 25 Years: The DREAM Study
Willem Tideman
Progression and Longitudinal Biometric Changes in Highly Myopic Eyes
Mingguang He
Oral 2【Session Room 1】12-Sep 9:35-10:35


Chris Hammond
(King’s College London)
Milly Tedja
(Ophthalmology and Epidemiology,
 Erasmus Medical Centre)
Genetic and Parental Factors of Myopia
Calvin C. P. Pang
Genetic Study of 542,934 Subjects Identifies Novel Genes and Genetic Mechanisms Predisposing to Refractive Error and Myopia
Christopher Hammond
Improving Prediction of Myopia using Information on Genetic Risk Factors
Pirro Hysi
Pathway-Specific Genetic Risk Scores Associated with High Myopia
Milly S. Tedja
Analysis of Genetic Networks Regulating Refractive Eye Development in Collaborative Cross Mice Reveals New Genes and Pathways Underlying Human Myopia
Andrei V. Tkatchenko
Oral 3【Session Room 1】12-Sep 15:28-17:16

Environmental Risk Factors

Seang-Mei Saw
(Singapore Eye Research Institute)
Pei-Chang Wu
(Kaohsiung Chang Gung Memorial Hospital)
A Systematic Review: The Role of Time Exposed to Outdoor Light for Myopia Prevalence and Progression
Leila S. Eppenberger
Outdoor Play, Playgrounds, and Myopia in Children
Clair Enthoven
Habitual Indoor and Outdoor Activity of Myopic and Non-Myopic University Students in the United States and Norway
Elise N. Harb
Comparison of Outdoor Exposure and Nearwork between Children with and without Parents with Myopia by Using Clouclip
Weizhong Lan
Outdoor Jogging and Myopia Progression in School Children from Rural Beijing: The Beijing Children Eye Study
Yin Guo
Myopia and Risk Factor Exposures within Academically-streamed Schools
Amanda N. French
Refractive Error Change among Schoolchildren with 1-Year Tablet Computer Use as Educational Tool in School
Jung Lo
Recent, but Not Past, Vitamin D Concentrations are Associated with Myopia in Young Adulthood
Gareth N. Lingham
Sleep Duration and Myopia Progression in a Four-year Follow-up of Chinese Children: The Anyang Childhood Eye Study
Shi-Fei Wei
Oral 4-1【Session Room 1】13-Sep 8:35-9:50

Animal Models and Basic Research I

Frank Schaeffel
(University of Tübingen)
Chi-Ho To
(The Hong Kong Polytechnic University)
Special Lecture: Genetically Modified Animal Models of Myopia
Terri Young
Reviewing Lens-induced Myopia in C57BL/6 Mice
Beerend Winkelman
Differential Wavelength Cues are Essential for Emmetropization in Tree Shrews
Timothy J. Gawne
Effects of Myopic-astigmatic Development on Retinal Functions in Chicken
Sonal A. Vyas
The Impact of Exposure to Multiple Episodes of Defocus on Chick Eye Growth
Pauline Kang
Amacrine Cells Expressing nNOS are Sensitive to the Sign of Defocus in the Mammalian Retina
Sally A. McFadden
Oral 4-2【Session Room 1】13-Sep 9:50-11:14

Animal Models and Basic Research II

Timothy Gawne
(University of Alabama at Birmingham)
Alexandra Benavente-Perez
(SUNY College of Optometry)
The Mechanism Study of Dopamine D2 Receptor Involving the Flickering Light Induced Myopia of Guinea Pigs
Shunmei Ji
Low Dose Atropine Does Not Influence Dopamine Release in Chickens
Kate Thomson
Atropine Distribution in the Chick Eye: Analysis using Mass Spectrometry and Immunoassays
Muthana H. Noori
Scleral Hif-1α Knock-down Shifted Refraction toward Hyperopia in Normal Environment but Suppressed Form-deprivation Myopia (FDM) Development in Mice
Xiangtian Zhou
Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia
Guoyun Zhang
Decreased Stiffness and Increased Permeability in Sclera of Myopic Mice
Dillon M. Brown
Two Quantitative High-frequency Ultrasound Methods to Assess Microstructural Changes in Guinea Pig Sclera
Jonathan Mamou
Oral 5【Session Room 1】13-Sep 11:14 -12:02

Accommodation/Binocular Vision

Lisa Ostrin
(University of Houston College of Optometry)
Sandra Wagner
(Eberhard Karls University Tuebingen)
Comparison of Different Techniques to Assess the Near Accommodation Responses
Ting Wang
Emmetropes and Myopes Differ Little in Their Accommodation Dynamics but Strongly in Their Ciliary Muscle Morphology
Sandra Wagner
Early Warning Effect of Accommodative Facility in the Occurrence of Myopia in Adolescents
Xiaoyan Yang
Comparison of Binocular Imbalance in Emmetropic and Myopic Volunteers under a Non-immersive Virtual Reality Platform
Jin Zeng
Oral 6【Session Room 1】13-Sep 16:05-17:41

Spectacles and Ortho K

Toshifumi Mihashi
(University of Tsukuba)
Sally McFadden
(University of Newcastle)
The Effect of Orthokeratology Compression Factor on Ocular Higher-order Aberrations
Jason K. Lau
Clinical Observation of Effect of Long-term Overnight Wearing of Orthokeratology Lenses on Myopia Progression and Ocular Safety in Adolescents
Yin Yang
Comparison of Myopia Progression between Children Wearing Three Types of Orthokeratology (Ortho-K) Lenses and Children Wearing Single Vision Glasses
Yo Nakamura
Comparisons of the Myopia Control Effects of Standard Design and Toric Design Orthokeratology Lenses
Zhao Chen
Influence of Change to Orthokeratology Induced Treatment Zone Diameter and Pupil Diameter on the Optics of the Cornea
Paul Gifford
A Pilot Study Comparing CRT Orthokeratology Lenses with Two Different Treatment Zone Sizes
Maria Liu
Anatomic Factors Contributed to Choroidal Thickening after Orthokeratology: Evidence from Image Binarization of SD-OCT
Jinyun Jiang
Atropine Combined with Orthokeratology (ACO) in the Treatment of Myopia: Change of Subfoveal Choroidal Thickness (SFChT)
Wenchen Zhao
Oral 7【Session Room 1】14-Sep 8:10-9:22

Multifocal CL

Padmaja Sankaridurg
(University of New South Wales)
Pauline Cho
(The Hong Kong Polytechnic University)
Optical and Neural Contribution in the Peripheral Retina to Myopia Control
Geunyoung Yoon
Central and Peripheral Visual Quality and Accommodation with Multifocal Contact Lenses
Linda Lundstrom
Accommodation Response with Multifocal Contact Lenses in Non-presbyopic Subjects
Martin Loertscher
The Adaptation and Acceptance of Defocus Incorporated Multiple Segments (DIMS) for Chinese Adolescents
Yiqiu Lu
Measured and Predicted Axial Elongation in the MiSight Clinical Trial
Paul Chamberlain
Efficacy of Myopia Control Contact Lenses (BHVI Extended Depth of Focus Contact Lens and MiSight) in a Contralateral Study Design
Padmaja Sankaridurg
Oral 8【Session Room 1】14-Sep 15:23-17:47

Pharmacological Approach, Potential Therapies and Others

Ian Morgan
(Australian National University)
Zhou Xiangtian
(Wenzhou Medical University)
Current and Emerging Pharmaceutical Interventions for Myopia
Kritchai Vutipongsatorn
Myopia Controle for Europeans: Evidence-based Protocol
Caroline C.W. Klaver
Two-Year Clinical Trial of the Low-concentration Atropine for Myopia Progression (LAMP) Study: 0.05% Atropine Remained the Optimal Concentration for Myopia Control
Jason C.S. Yam
The Efficacy of 0.01% Atropine Ophthalmic Solution for Controlling the Progression of Childhood Myopia (ATOM-J) - Randomized Controlled Trial
Osamu Hieda
Efficacy of Low Dose Atropine in Indian Progressive Myopes
Viswanathan Sivaraman
The Efficacy and Safety of Topical 0.01% Atropine in Controlling Near-work Induced Transient Myopia
Lei Guo
A Gold Standard for Myopia Control Efficacy: Cumulative Absolute Reduction of Axial Elongation (CARE)
Mark Bullimore
Consistency of Absolute Myopia Control Treatment Effect Across Age (Or Why Tom Aller Got 80% Treatment Efficacy!)
Noel A. Brennan
Temporal Considerations in Myopia Control Efficacy
Jaclyn V. Hernandez
7-methylxanthine (7-mx) for Myopia Control - Five-year Data
Klaus Trier
MyopiaX: Invisible Myopia Treatment using Visible Light
Hamed Bahmani
Results with Snyder- Thompson Posterior Scleral Reinforcement in Progressive, High Myopic Children in Hungary
Noemi Szell
Oral 9【Session Room 1】15-Sep 8:05-8:53

Ocular Biometry

Christine Wildsoet
(University of California, Berkeley)
Rigmor Baraas
(University of South-Eastern Norway)
Change of The Refractive Status after Cycloplegia and Its Related Factors in Children Aged 6-12
Bei Du
Mathematical Estimation of Axial Length using Routine Optometric Data in the Absence of Formal Biometry
Nabin Paudel
Effect of Chromatic and Monochromatic Aberrations on Detecting the Sign of Defocus in the Periphery
Petros Papadogiannis
Salivary Melatonin, Sleep and Activity: Myopes Compared to Non-Myopes
Sarah C. Flanagan
Oral 10【Session Room 1】15-Sep 8:53-10:17

Pathologic Myopia/Ocular Circulation and Eye Shape

Yasushi Ikuno
(Ikuno Eye Center)
Yuxin Fang
(Tokyo Medical and Dental University)
Watching Spatially Filtered Movies That Enhance ON or OFF Stimulation Changes Choroidal Thickness
Frank Schaeffel
Choroidal Thickness in Australian Indigenous Children
Scott A. Read
Representation of the Fundus Shape using Legendre Polynomial Expansions of RPE Segmentation Data Obtained by the OCT with Auto Alignment Function
Toshifumi Mihashi
Projections of Myopia-associated Eye Diseases
Xu Cheng
Retinal Complications in High Myopia in Europeans
Annechien E.G. Haarman
Comparison of Clinical Features in Highly Myopic Eyes with and without Posterior Staphyloma evaluated with Ultrawide-Field Swept-Source OCT
Takashi Watanabe
Long-Term Outcomes and Complications of Foveola-nonpeeling/Fovea-sparing Internal Limiting Membrane Surgery of Myopic Traction Maculopathy
Tzyy-Chang Ho


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Rapid fire Presentations

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Medical Equipment Exhibition, Book Exhibition

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