CURRICCULUM VITAE
Education and Training:
M.D. 1997, Tokyo Medical and Dental University, Tokyo, Japan.
Professional Experience:
4/97-3/99: Resident in Ophthalmology, Tokyo Medical and Dental University
4/99-3/01: Fellow in Ophthalmology, Tokyo Metropolitan Hiroo Hospital
4/01-5/03: Fellow in Ophthalmology, Tokyo Medical and Dental University
6/03-3/05: Assistant Professor of Ophthalmology, Tokyo Medical and Dental University
4/05-4/06: Clinical Fellow, Mitsui Memorial Hospital, Tokyo, Japan
5/06-9/07: Assistant Professor of Ophthalmology, Chiba University Graduate School of Medicine, Chiba, Japan
10/07-3/10: Research Fellow, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
4/10-: Assistant Professor of Ophthalmology, Chiba University Graduate School of Medicine
6/17-: Associate Professor of Ophthalmology, Chiba University Graduate School of Medicine
Research Interests:
Myopic Retinoschisis
Myopic retinal disorders including myopic choroidal neovascularization and myopic schisis are still not treated completely. Their management is still controversial and need further investigations. Dr. Baba is interested in myopic schisis and has reported its prevalence and characteristic in highly myopic eyes. [AJO 2002] Currently, the most common approach to myopic schisis is pars plana vitrectomy with ILM peeling. However, this procedure sometimes causes postoperative development of full-thickness macular hole which is hard to be treated even with repeated vitrectomy. Moreover, the retinal damage by ILM peeling has to be taken into account. We have reported the efficacy of scleral buckling surgery using macular plombe to treat myopic schisis. [AJO2005] Recently we have tried scleral imbrication combined with vitrectomy. The functional and anatomical outcome was favorable although ILM peeling was not performed.[Retina2016]
Kaoru Fujinami, MD PhD, is a clinical ophthalmologist and a Clinical Geneticist, working for the Laboratory of Visual Physiology, and Department of Ophthalmology/Medical Genetics Center, Tokyo Medical Centre (TMC). He is also affiliated with Genetics, University College London (UCL) Institute of Ophthalmology associated with Moorfields Eye Hospital.
He has focused on inherited retinal disorder (IRD) over the last 15 years. He has been working on improving understanding of IRD both in clinical and molecular genetic aspects, including clinical characterization, electrophysiologic assessment, molecular genetic analysis, genotype-phenotype association/correlation, and introducing cutting-edge treatments.
TMC leads many nationwide and international genetic research consortia, including the Japan Eye Genetics Consortium (JEGC), National Hospital Organization Network Research Group (NHO-NRG), and East Asia Inherited Retinal Disease Society (EAIRDS). These consortia have large cohorts in Japan/East Asia, and analyses of the obtained big data (N>3000 Japanese subjects, N>6000 East Asian subjects) yield novel findings, including ethnicity-specific phenotype and genotype. In 2020, the TMC team started a gene augmentation trial targeting RPE65-associated retinopathy, the first in East Asia. In addition, therapeutic options with advanced technology have been developed under intra- and international industry-government-academia collaborations.Dr. Yasuhiko Hirami is currently Vice President of Kobe City Eye Hospital and a visiting researcher of Laboratory of Retinal Regeneration, RIKEN Center for Developmental Biology. His research focuses on clinical application of regenerative medicine and cell transplantation for retinal degenerative disease.
Vice President, Kobe City Eye Hospital (2019-present)
Chief Ophthalmologist, Kobe City Eye Hospital (2017-2018)
Chief Ophthalmologist, Division of ophthalmology, Department of Translational Research, Institute of Biomedical Research and Innovation Hospital (2008-2017)
Research Associate, Laboratory of Retinal Regeneration, RIKEN Center for Developmental Biology (2007-2008)
Resident, Department of Ophthalmology, Kurashiki Central Hospital (2000-2003)
Resident, Department of Ophthalmology, Kyoto University Hospital (1999-2000)
Affiliation:
Department of Surgery-related, Division of Ophthalmology, Kobe University Graduate School of Medicine.
Professional Affiliations
2001-present Japanese Ophthalmological Society,
2001-present The vitreoretina society of Japan
2005-present Japanese society of ophthalmic surgeon
Major Research Interest
Vitreo-retinal surgery
1985 Graduated from Kyoto University Medical School
1985-1986 Residency at Kyoto University Hospital and Kitano Hospital in Osaka
1989-1991 Research fellowship in the group of Prof Michael F. Marmor at Stanford University, USA
1992 PhD (Ophthalmology) from Kyoto University
1993-1997 Assistant Professor in Kyoto University
1997-2000 Director of Dept. of Ophthalmology in Shiga Prefectural Hospital
2000-2005 Director of Dept. of Ophthalmology in Otsu Red Cross Hospital
2005-2009 Associate Professor & Vice Chairman of Dept. of Ophthalmology in Kyoto University
2009-2012 Director of Dept. of Ophthalmology in Amagasaki Prefectural Hospital
2012- Director of Dept. of Ophthalmology in National Hospital Organization Kyoto Medical Center Clinical Professor in Kyoto University
Subspecialties: vitreoretinal surgery, endoscopic ocular surgery physiology of retinal pigment epithelium, retinal adhesion
< Work Experience >
2012- Managing Director, Dept of Ophthalmology, National Hospital Organization, Kyoto Medical Center Clinical Professor, Dept of Ophthalmology, Kyoto University
2009-2012 Managing Director, Dept of Ophthalmology, Hyogo prefectural Hospital
2005-2009 Vice Professor, Dept of Ophthalmology, Kyoto University
2000-2005 Managing Director, Dept of Ophthalmology, Otsu Red Cross Hospital
1997-2000 Managing Director, Dept of Ophthalmology, Shiga Prefectural Hospital
1993-1997 Associate Professor, Dept of Ophthalmology, Kyoto University
< Education >
1987-1992 PhD course, Kyoto University School of Medicine
1989-1991 Post-doctoral course, Stanford University School of Medicine (Dr. Marmor MF)
1979-1985 Kyoto University School of Medicine
Dr. Kita’s clinical research interests include retinal detachments, trauma, and techniques in vitreoretinal surgery, with a particular interest in 3D hybrid vitrectomy using endoscope and wide-angle viewing system recently. She developed a new CL for observing fundus with a noncontact wide-angle viewing system (Clin Ophthalmol. 2017), which is nicknamed ‘Mihorin Slim’ and is used widely in Japan.
Dr. Kita is the organizer of Ophthalmic meetings such as Cold Cases in Ophthalmology, Fight Club in Retinal Detachment, and Ophthalmic Collaboration Network at FSM.
Dr. Kita authored and co-authored over 320 articles and book chapters. She gave over 870 presentations and lectures.
Present Position: Professor & Chairman
Department: Ophthalmology
Faculty: Medicine
Institution: Tokushima University Graduate School
EDUCATION and DEGREES
1987 M.D., School of Medicine, Hokkaido University, Japan
2000 Ph.D., Toho University, Japan
CERTIFIED SPECIALISTS
1993 Japanese Ophthalmological Society
MAIN CLINICAL INTERESTS
Vitreoretinal diseases, Vitreoretinal surgery
Yoko Ozawa M.D., Ph.D. works as a Professor and Director of Department of Ophthalmology, St. Luke’s International University and Hospital. She is a specialist of vitreal, retinal, and macular diseases, and a chief vitreo-retinal surgeon and medical retina clinician. She also works as a Lab Chief of the Laboratory of Retinal Cell Biology (RCB lab). Her recent research interest is the aging and neuroprotection of the retina, and its association with oxidative stress and inflammation. One of her missions is to find a neuroprotective treatment for the retinal diseases, such as age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa.
PROFESSIONAL BACKGROUND (EMPLOYMENT HISTORY)
Teaching Experience
Associate Professor - Department of Ophthalmology, Jichi Medical University 2017 - present
Assistant Professor - Department of Ophthalmology, Jichi Medical University 2012 - 2017
Specialist in artificial intelligence.
Education
Doctor of Philosophy - Graduate School of Medicine, The University of Tokyo, Tokyo, Japan 2004 - 2008
Doctor of Medicine - Faculty of Medicine, The University of Tokyo, Tokyo, Japan 1995 - 2001
Publications
Association between visual field damage and corneal structural parameters. Lavric A, Popa V, Takahashi H, Hazarbassanov RM, Yousefi S. Sci Rep. 2021 May 24;11(1):10732.
Shortening of Interpupillary Distance after Instillation of Topical Prostaglandin Analog Eye Drops. Sano I, Takahashi H, Inoda S, Sakamoto S, Arai Y, Takahashi Y, Ohkubo A, Kawashima H, Mayama C Am J Ophthalmol. 2019 Oct;206:11-16.
Changes in multiple cytokine concentrations in the aqueous humour of neovascular age-related macular degeneration after 2 months of ranibizumab therapy. Sakamoto S, Takahashi H, Tan X, Inoue Y, Nomura Y, Arai Y, Fujino Y, Kawashima H, Yanagi Y. Br J Ophthalmol. 2018 Apr;102(4):448-454.
Applying artificial intelligence to disease staging: Deep learning for improved staging of diabetic retinopathy. Takahashi H, Tampo H, Arai Y, Inoue Y, Kawashima H. PLoS One. 2017 Jun 22;12(6):e0179790.
Relationship between visual prognosis and delay of intravitreal injection of ranibizumab when treating agerelated macular degeneration. Takahashi H, Ohkubo Y, Sato A, Takezawa M, Fujino Y, Yanagi Y, Kawashima H. Retina. 2015 Jul;35(7):1331-8.
Awards
NTT Data, DBJ, and Jetro Award as DeepEyeVision CEO, Entrepreneur Expo 2020. Mar 2021
Microsoft Japan Award as DeepEyeVision CEO, Hongo AI 2020. Dec 2020
Relevant Experience
CEO - DeepEyeVision Inc.: The 1st certified venture company of Jichi Medical University. 2019 - present
CURRENT POSITION
Associate Professor, Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
EDUCATIONAL AND PROFESSIONAL HISTORY
1992-1998 Nagoya University School of Medicine (M.D.)
1998-2000 Resident in Ekisaikai Hospital (Clinical Medicine), Nagoya, Japan
2000-2001 Resident in Nagoya University Hospital
2001-2004 Clinical and Research Fellowship Program (Retina) at Nagoya University Graduate
School of Medicine (Ph.D., Medical Science)
2004-2005 Special Research Fellowship Program (Retina)
2005-2007 Research Fellow, Ophthalmology, Johns Hopkins University
(Prof. Peter A Campochiaro)
2007-2020 Assistant Professor, Ophthalmology, Nagoya University Graduate
School of Medicine
2021- Associate Professor, Ophthalmology, Nagoya University Graduate
School of Medicine
MEMBERSHIP AND BOARD
The Association for Research in Vision and Ophthalmology
The International Society for Clinical Electrophysiology of Vision
The Japanese Ophthalmological Society
The Vitreo-retinal Society of Japan
The Japanese Society for Clinical Electrophysiology of Vision (Board Member)
AWARDS AND HONORS
2014 Retinitis Pigmentosa Research Award (Japan)
2015 Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder (Japan)
MAJOR RESEARCH INTERESTS
• Physiology and pathophysiology of retina and visual system
• Electrophysiology in animal models and human eye diseases
• Diagnosis and research for disease mechanism in inherited retinal diseases
• Vitreo-retinal surgery
• Imaging of retina
LIST OF REPRESENTATIVE PEER-REVIEWED PUBLICATIONS
Ueno S et al.: Selective amplitude reduction of the PhNR after macular hole surgery: ganglion cell damage related to ICG-assisted ILM peeling and gas tamponade. Investigative ophthalmology & visual science, 47:3545-3549, 2006
Ueno S, et al. : Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. Journal of cellular physiology, 217:13-22, 2008
Ueno S, et al.: Clinical course of paraneoplastic retinopathy with anti-trpm1 autoantibody in Japanese cohort. Retina, 39:2410-2418, 2019
homepage
https://www.researchgate.net/profile/Yasuo_Yanagi
https://scholar.google.ca/citations?user=6KyEIvYAAAAJ&hl=en
Current Appointment Details
Institution of Primary Appointment: Director, Ohana-Jaya Eye Clinic
Secondary Appointments
Adjunct Professor Duke NUS, Singapore Eye Research Institute, Singapore National Eye Centre
Adjunct Professor, Yokohama City University, Kanagawa, Japan
Adjunct Professor, Department of Ophthalmology, Asahikawa Medical University
Director, DeepEyeVision
Professional Training & Academic Career (Employment History)
Post Doc, Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, Postdoctoral Fellow, 1/4/2001-31/32003
Research Fellow, Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine The University of Tokyo, Tokyo, Japan, 1/4/2003-31/3/2004
Assistant Professor, Ophthalmology and Visual Correction, The University of Tokyo Hospital, Tokyo, Japan, Assistant Professor, 1/4/2004-31/3/2012
Assistant Professor, Department of Ophthalmology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan, Assistant Professor, 1/4/2012-31/3/2015
Singapore National Eye Centre, Senior Ophthalmologist, 1/7/2015-31/9/2021
Singapore Eye Research Institute, Clinician Scientist, 1/7/2015-current
Adjunct Lecturer, Jichi Medical School, Adjunct Lecturer, 1/7/2015-31/3/2021
Associate Professor, Duke NUS Medical School, Associate Professor, 1/1/2016-current
Adjunct Professor,Yokohama City University,Adjunct Professor, 1/4/2020-current